Investigations on searching alternative methods of assessment of physiological state of biological systems in 2000 led to the development of new apparatus complex "Bioscope" capable to react distantly on the approaching of living objects (plants, animals, human).
The device is simple in design, and its working principle is based on evaluation of the intensity of light scattered from the sensor - the glass plate covered by a thin opaque material. Structurally, "Bioscope" is optically and electrically isolated from the environment and the approaching of the various objects to the device obviously would not have to alter its readings. For inanimate objects with the ambient temperature, the device is insensitive. However, the instrument responds to the presence of a human at a distance of 5-6 meters. The studies have revealed that among inanimate objects, water exhibits a special position, and in the presence of water near the "Bioscope", the expressed signal changes are observed, even if water is placed in hermetic capsule.
Numerous experiments on the influence of stress, as well as the effect of number of pharmacological agents on animals have shown high sensitivity and specificity of remote "Bioscope" signals to the change of physiological state of animal. The data are obtained that create the preconditions for the practical use of hardware complex "Bioscope" for early prediction of infection and the beginning of the formation of pathological processes in the body.
Now, work has begun to assess the possibility of using hardware complex "Bioscope" for early prediction of the of the cancer formation in humans.
In numerous experiments it has been proved unambiguously that the nature of observed effects is not connected with thermal, electromagnetic or acoustic fields. The readings of device are always reliable and repeatable. Thus performed experiments lead to the conclusion about ability of biological systems to exert influence on the surrounding objects. Such interactions have quantum mechanical nature, they are formed into biological system and can exert definitely influence on the direction of all biochemical processes in organism. The revealed phenomena are not considered in mainstream since and this brings to the necessity of changing of some generally accepted scientific concepts.
Various biological objects affect the "Bioscope’s" readings in different degrees, at the same time the apparatus signals depend on the changing of their physiological state. This indicates on the possibility of application of developed device for non-invasive assessment of the functional state of biological systems in a variety of medical and biological research.
The advantages of using "Bioscope" are obvious: it is non-damaging registration of any part of the body convenient for carrying out the experiment, the possibility of continuous assessment of the functional state of the awake organism body, no need for the screening of external electric or magnetic fields.
It is worth to note also that the experiments can be carried out in compliance with all generally accepted ethical treatment of animals.
EARLY REVEALING OF INFECTION OF WHITE MICE WITH SKIN CANCER
Spectral distribution of "Bioscope" signals before and after infection with skin cancer.
1 - one day before infection
2 - one day after infection
Abscissa axis – oscillation frequency of "Bioscope” signals
Ordinate axis – spectral power in relative units
The next day after the induction of skin cancer, in the spectral distribution of the signals for "Bioscope" is formed pronounced "cancerous peak", which is maintained until the death of the mice. In mice that were also infected, but not dead, "cancerous peak" practically wasn't formed.
Modern instrumental approaches intended to assessment of physiological state of organism are directed on registration its various physical-chemical characteristics. It is assumed that after their cumulative analysis one can be judged on the physiological state of the organism as a whole. The uniqueness of "Bioscope" is that unlike other instrumental approaches its signals are initially reflect the state of the whole system. Therefore,to assess the state of organism simultaneous use of the both hardware complex "Bioscope" and conventional instrumental approaches is required to form physiologically meaningful interpretation of the "Bioscope" signals. With this purpose in the laboratory were conducted scientific and technical works that led to the design and construction of standard equipment, which can also be used in a number of other biomedical centers to carry out their own research.
Instruments are designed using modern microprocessor technologies, they are compact and can be used in any room. Powering of the equipment and information transfer to computer are made through the USB port. Registration and analysis of devices’ signal are carried out with the use of modern software packages LabView. Devices were tested in various biomedical centers and received a positive evaluation and recommendations for their implementation in Armenia.
|SOME SOFTWARE DEVELOPED BY LABORATORY TEAM
|“Bioscope” signal analysis
|Cardiograph’s signal analysis
|12-channel cardiograph’s signal analysis
|Analysis of behavioral reactions of laboratory animals